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Studies in vitiligo have shown that the skin surrounding vitiligo lesions is enriched with CD8 + T RM populations expressing CD69 and CD103 during the stable and active phase ( RM cells produce perforin, Granzyme B, and IFN- upon interleukin-15 (IL-15) stimulation and maintain disease in cooperation with recirculating memory T (TRCM) cells

Keith JM, Jones WM, Tichenor M, Liu J, Seierstad M, Palmer JA